Article
Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 Oct 2008
Gowing Genevíève, Philips Thomas, Van Wijmeersch Bart, Audet Jean-Nicolas, Dewil Maarten, Van Den Bosch Ludo, Billiau An D, Robberecht Wim, Julien Jean-Pierre
Abstract excerpt
Microglial activation is a hallmark of all neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Here, a detailed characterization of the microglial cell population within the spinal cord of a mouse model of familial ALS was performed. Using flow cytometry, we detected three d...
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