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Article

[ALS and microglia--a player for non-cell-autonomous neuron death].

Brain and nerve = Shinkei kenkyu no shinpo - 1 Oct 2007

Yamanaka Koji, Yamashita Hirofumi

Abstract excerpt

Dominant mutation in the gene of superoxide dismutase 1 (SOD1) leads to amyotrophic lateral sclerosis (ALS), an adult-onset progressive fatal motor neuron disease. Recent progress in research on ALS has been made by the use of transgenic mouse model of familial ALS, which expresses mutant form of SOD1 and recapitulates the phenotype and pathology of motor neuron disease. There is accumulating evidence indicating...

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Identifiers

PMID: 17969357

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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