Article
Cyclooxygenase-2, multidrug resistance 1, and breast cancer resistance protein gene polymorphisms and inflammatory bowel disease in the Danish population.
Scandinavian journal of gastroenterology - 1 Jan 2009
Østergaard Mette, Ernst Anja, Labouriau Rodrigo, Dagiliené Enrika, Krarup Henrik B, Christensen Mariann, Thorsgaard Niels, Jacobsen Bent A, Tage-Jensen Ulrik, Overvad Kim, Autrup Herman, Andersen Vibeke
Abstract excerpt
OBJECTIVE: Crohn's disease (CD) and ulcerative colitis (UC) are characterized by an impaired mucosal defence to normal constituents of the intestinal flora and a dysregulated inflammatory response. The purpose of the study was to investigate whether single nucleotide polymorphisms (SNPs) in genes involved in these processes were associated with CD and UC. MATERIAL AND METHODS: Allele frequencies of the...
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