Article
MDR1 gene: susceptibility in Spanish Crohn's disease and ulcerative colitis patients.
Inflammatory bowel diseases - 1 Jan 2006
Urcelay Elena, Mendoza Juan L, Martín M Carmen, Mas Ana, Martínez Alfonso, Taxonera Carlos, Fernandez-Arquero Miguel, Díaz-Rubio Manuel, de la Concha Emilio G
Abstract excerpt
BACKGROUND: The multidrug resistance MDR1 gene codes for a membrane transporter associated with inflammatory bowel disease. The polymorphism Ala893Ser/Thr (G2677T/A) previously showed significant association with Crohn's disease (CD) and the Ile1145Ile (C3435T) with ulcerative colitis (UC). We st...
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