Article
MDR1 gene polymorphisms are associated with ulcerative colitis in a cohort of Serbian patients with inflammatory bowel disease.
PloS one - 1 Jan 2018
Mijac Dragana, Vukovic-Petrovic Irena, Mijac Vera, Perovic Vladimir, Milic Natasa, Djuranovic Srdjan, Bojic Daniela, Popovic Dragan, Culafic Djordje, Krstic Miodrag, Jankovic Goran, Pravica Vera, Markovic Milos
Abstract excerpt
BACKGROUND: Inflammatory bowel disease (IBD) is a chronic disease of unknown etiology in which genetic factors contribute to development of disease. Single nucleotide polymorphisms (SNPs) in multidrug resistance 1 (MDR1) gene encoding transporter P-glycoprotein have been associated with IBD, but their role in disease susceptibility remains unclear. Therefore, the aim of this study was to investigate the...
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