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Article

Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease?

Inflammatory bowel diseases - 1 Mar 2012

Zintzaras Elias

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD) is a complex disease with a genetic background. Crohn's disease (CD) and ulcerative colitis (UC) are the two main types of IBD. There is indication that variants in the MDR1 gene are associated with development of IBD. However, the 20 published genetic association studies (GAS) for the three most popular variants in the MDR1 gene (C3435T, G2677T/A, and C1236T) have...

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Identifiers

PMID: 21887726
DOI: 10.1002/ibd.21728

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ABCB1

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Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease?PMID 21887726Read ↗

Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

MDR1 polymorphisms are associated with inflammatory bowel disease in a cohort of Croatian IBD patients.Semantic proximity Read ↗

MDR1 C3435T polymorphism and inflammatory bowel disease risk: a meta-analysis.Semantic proximity Read ↗

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Genetic analysis of MDR1 and inflammatory bowel disease reveals protective effect of heterozygous variants for ulcerative colitis.Semantic proximity Read ↗

Multidrug resistance 1 gene polymorphism and susceptibility to inflammatory bowel disease.Semantic proximity Read ↗

Associations between ABCB1/MDR1 gene polymorphisms and Crohn's disease: a gene-wide study in a pediatric population.Semantic proximity Read ↗

MDR1 gene polymorphisms are associated with ulcerative colitis in a cohort of Serbian patients with inflammatory bowel disease.Semantic proximity Read ↗

Effect of the C3435T polymorphism of the multidrug resistance 1 gene on the severity of inflammatory bowel disease in Iranian Azeri Turks.Semantic proximity Read ↗

Absence of association between the multidrug resistance (MDR1) gene and inflammatory bowel disease.Semantic proximity Read ↗

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