Article
ATP-binding cassette transporter ABCG2 (BCRP) and ABCB1 (MDR1) variants are not associated with disease susceptibility, disease phenotype response to medical therapy or need for surgeryin Hungarian patients with inflammatory bowel diseases.
Scandinavian journal of gastroenterology - 1 Jun 2007
Fischer Simon, Lakatos Peter Laszlo, Lakatos Laszlo, Kovacs Agota, Molnar Tamas, Altorjay Istvan, Papp Maria, Szilvasi Aniko, Tulassay Zsolt, Osztovits Janos, Papp Janos, Demeter Pal, Schwab Richard, Tordai Attila, Andrikovics Hajnalka
Abstract excerpt
OBJECTIVE: MDR1 (ABCB1), a member of the ATP-binding cassette (ABC) transporters, is an attractive candidate gene for the pathogenesis of inflammatory bowel diseases (IBD) and perhaps for response to therapy. Since limited data are available on MDR1 and ABCG2 polymorphisms in East European IBD pa...
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