Article
MDR1 polymorphisms are associated with inflammatory bowel disease in a cohort of Croatian IBD patients.
BMC gastroenterology - 27 Mar 2013
Brinar Marko, Cukovic-Cavka Silvija, Bozina Nada, Ravic Katja Grubelic, Markos Pave, Ladic Agata, Cota Marijana, Krznaric Zeljko, Vucelic Boris
Abstract excerpt
BACKGROUND: Inflammatory bowel diseases (IBD) are chronic diseases of unknown etiology and pathogenesis in which genetic factors contribute to development of disease. MDR1/ABCB1 is an interesting candidate gene for IBD. The role of two single nucleotide polymorphisms, C3435T and G2677T remains unclear due to contradictory results of current studies. Thus, the aims of this research were to investigate the...
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