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Article

Genetic analysis of MDR1 and inflammatory bowel disease reveals protective effect of heterozygous variants for ulcerative colitis.

Inflammatory bowel diseases - 1 Dec 2009

Huebner Claudia, Browning Brian L, Petermann Ivonne, Han Dug Yeo, Philpott Martin, Barclay Murray, Gearry Richard, McCulloch Alan, Demmers Pieter, Ferguson Lynnette R

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the multidrug transporter MDR1 have been associated with inflammatory bowel disease (IBD) in different studies. However, the data are highly controversial. Recently, 6 haplotype tagging SNPs (tSNPs), representing the haplotype variations of the MDR1 gene, were identified. The aims of this study were to genotype these variants and correlate them to disease...

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Identifiers

PMID: 19685447
DOI: 10.1002/ibd.21019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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