Article
Genetic analysis of MDR1 and inflammatory bowel disease reveals protective effect of heterozygous variants for ulcerative colitis.
Inflammatory bowel diseases - 1 Dec 2009
Huebner Claudia, Browning Brian L, Petermann Ivonne, Han Dug Yeo, Philpott Martin, Barclay Murray, Gearry Richard, McCulloch Alan, Demmers Pieter, Ferguson Lynnette R
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in the multidrug transporter MDR1 have been associated with inflammatory bowel disease (IBD) in different studies. However, the data are highly controversial. Recently, 6 haplotype tagging SNPs (tSNPs), representing the haplotype variations of th...
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