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Article

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis.

FEBS letters - 15 Oct 2008

Ishikawa Kaori, Hashizume Osamu, Koshikawa Nobuko, Fukuda Sayaka, Nakada Kazuto, Takenaga Keizo, Hayashi Jun-Ichi

Abstract excerpt

We addressed the issue of whether enhanced glycolysis caused by mtDNA mutations independently induces metastasis in tumor cells using mtDNA transfer technology. The resultant trans-mitochondrial cybrids sharing the same nuclear background of poorly metastatic carcinoma P29 cells, P29mtA11 and P29mtDelta cybrids, possessed mtDNA with a G13997A mutation from highly metastatic carcinoma A11 cells and mtDNA with a...

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Identifiers

PMID: 18805414
DOI: 10.1016/j.febslet.2008.09.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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