Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial DNA mutations regulate metastasis of human breast cancer cells.

PloS one - 1 Jan 2011

Imanishi Hirotake, Hattori Keisuke, Wada Reiko, Ishikawa Kaori, Fukuda Sayaka, Takenaga Keizo, Nakada Kazuto, Hayashi Jun-ichi

Abstract excerpt

Mutations in mitochondrial DNA (mtDNA) might contribute to expression of the tumor phenotypes, such as metastatic potential, as well as to aging phenotypes and to clinical phenotypes of mitochondrial diseases by induction of mitochondrial respiration defects and the resultant overproduction of re...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Cell Line, Tumor
Share to Cell Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Genome, Human

Share to Hybrid Cells

Share to Neoplasm Metastasis

Source

Open in PubMed Open full text

Identifiers

PMID: 21853128
DOI: 10.1371/journal.pone.0023401
PMCID: PMC3154938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21853128-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial DNA mutations regulate metastasis of human breast cancer cells.PMID 21853128Read ↗

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.Semantic proximity Read ↗

Trading mtDNA uncovers its role in metastasis.Semantic proximity Read ↗

A novel function of mtDNA: its involvement in metastasis.Semantic proximity Read ↗

[Mitochondria theory of tumor metastasis: ROS-generating mtDNA mutations reversibly regulate tumor cell metastasis].Semantic proximity Read ↗

Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasisSemantic proximity Read ↗

Mitochondrial DNA in Tumor Initiation, Progression, and Metastasis: Role of Horizontal mtDNA Transfer.Semantic proximity Read ↗

Specific mtDNA mutations in mouse carcinoma cells suppress their tumor formation via activation of the host innate immune system.Semantic proximity Read ↗

Mitochondrial Haplotype of the Host Stromal Microenvironment Alters Metastasis in a Non-cell Autonomous Manner.Semantic proximity Read ↗

"ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis"--a critical commentary.Semantic proximity Read ↗

Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.Semantic proximity Read ↗

Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs.Semantic proximity Read ↗

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.