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Article

A novel function of mtDNA: its involvement in metastasis.

Annals of the New York Academy of Sciences - 1 Jul 2010

Ishikawa Kaori, Hayashi Jun-Ichi

Abstract excerpt

It has been controversial whether mtDNA mutations are responsible for oncogenic transformation (normal cells to develop tumors) and for malignant progression (tumor cells to develop metastases). To clarify this issue, we created transmitochondrial cybrids with mtDNA exchanged between mouse tumor...

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Share to Cell Line, Tumor
Share to Cell Transformation, Neoplastic
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

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Share to Models, Biological

Share to Neoplasm Metastasis

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Source

Identifiers

PMID: 20649537
DOI: 10.1111/j.1749-6632.2010.05616.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20649537-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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