Investigation of the tryptophan hydroxylase 2 gene in bipolar I disorder in the Romanian population.

doi:10.1097/YPG.0b013e3283053045

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Article

Investigation of the tryptophan hydroxylase 2 gene in bipolar I disorder in the Romanian population.

Psychiatric genetics - 1 Oct 2008

Grigoroiu-Serbanescu Maria, Diaconu Carmen C, Herms Stefan, Bleotu Coralia, Vollmer Jennifer, Mühleisen Thomas W, Prelipceanu Dan, Priebe Lutz, Mihailescu Radu, Georgescu Marie-Jana, Sima Dorina, Grimberg Mihaela, Nöthen Markus M, Cichon Sven

Abstract excerpt

OBJECTIVE: Since the discovery of the tryptophan hydroxylase 2 gene (TPH2) several studies reported the association of TPH2 genetic variation with bipolar I (BPI) disorder. Our first objective was to replicate the recently described association of a rare functional single nucleotide polymorphism (SNP) (rs17110563) and of a haplotype covering the 5' region of TPH2 with BPI in a sample from the Romanian population....

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Identifiers

PMID: 18797398
DOI: 10.1097/YPG.0b013e3283053045

Genes

BPI
TPH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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