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Article

No association between TPH2 gene polymorphisms and ADHD in a UK sample.

Neuroscience letters - 29 Jan 2007

Sheehan Karen, Hawi Ziarih, Gill Michael, Kent Lindsey

Abstract excerpt

Tryptophan Hydroxylase 2 (TPH2) is the rate-limiting enzyme in the biosynthesis of serotonin which is exclusively expressed in the brain. Recent molecular studies reported significant association between markers mapped to TPH2 and psychiatric conditions including ADHD. We have examined four single nucleotide polymorphisms (SNPs) two of which (rs1843809, rs1386493) were reported to associate with ADHD in an Irish...

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Source

Identifiers

PMID: 17123708
DOI: 10.1016/j.neulet.2006.10.043

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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