Article
The chromatin remodelers ISWI and ACF1 directly repress Wingless transcriptional targets.
Developmental biology - 1 Nov 2008
Liu Yan I, Chang Mikyung V, Li Hui E, Barolo Scott, Chang Jinhee L, Blauwkamp Tim A, Cadigan Ken M
Abstract excerpt
The highly conserved Wingless/Wnt signaling pathway controls many developmental processes by regulating the expression of target genes, most often through members of the TCF family of DNA-binding proteins. In the absence of signaling, many of these targets are silenced, by mechanisms involving TCFs that are not fully understood. Here we report that the chromatin remodeling proteins ISWI and ACF1 are required for...
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