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Article

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway.

Genes & development - 1 Aug 1998

Kao H Y, Ordentlich P, Koyano-Nakagawa N, Tang Z, Downes M, Kintner C R, Evans R M, Kadesch T

Abstract excerpt

The Delta-Notch signal transduction pathway has widespread roles in animal development in which it appears to control cell fate. CBF1/RBP-Jkappa, the mammalian homolog of Drosophila Suppressor of Hairless [Su(H)], switches from a transcriptional repressor to an activator upon Notch activation. The mechanism whereby Notch regulates this switch is not clear. In this report we show that prior to induction...

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Identifiers

PMID: 9694793
DOI: 10.1101/gad.12.15.2269
PMCID: PMC317043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A histone deacetylase corepressor complex regulates the Notch signal transduction pathway.PMID 9694793Read ↗

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Trimethylation and Acetylation of β-Catenin at Lysine 49 Represent Key Elements in ESC Pluripotency.Semantic proximity Read ↗

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