Article
The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis.
Genes & development - 1 Nov 2005
Badenhorst Paul, Xiao Hua, Cherbas Lucy, Kwon So Yeon, Voas Matt, Rebay Ilaria, Cherbas Peter, Wu Carl
Abstract excerpt
Drosophila NURF is an ISWI-containing ATP-dependent chromatin remodeling complex that regulates transcription by catalyzing nucleosome sliding. To determine in vivo gene targets of NURF, we performed whole genome expression analysis on mutants lacking the NURF-specific subunit NURF301. Strikingly, a large set of ecdysone-responsive targets is included among several hundred NURF-regulated genes. Null Nurf301...
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