Genetic and molecular approach for breeding and use of laboratory fish for the detection of agents with carcinogenic and/or promoting activity.

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Article

Genetic and molecular approach for breeding and use of laboratory fish for the detection of agents with carcinogenic and/or promoting activity.

Bulletin du cancer - 1 Jan 1991

Anders A, Zechel C, Schlatterer B, Gröger H, Schmidt D, Smith A, Anders F

Abstract excerpt

Xiphophorine fish from wild populations are insusceptible to develop neoplasia. In contrast, certain backcrosses of Xiphophorus maculatus (platyfish) with Xiphophorus helleri (swordtail) as the recurrent parent, produce offspring that develop neoplasia in a Mendelian fashion. We concentrated our...

Topics

Animals
Carcinogens
Cell Transformation, Neoplastic
Crosses, Genetic
Cyprinodontiformes
Gene Expression Regulation, Neoplastic
Melanoma
Models, Biological
Mutation
Oncogenes

Source

Open in PubMed

Identifiers

PMID: 1878604

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1878604-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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