[Attempts at analyzing the initiation of the initial processes of carcinogenesis based on the Xiphophorus melanoma model].

Article

[Attempts at analyzing the initiation of the initial processes of carcinogenesis based on the Xiphophorus melanoma model].

Archiv fur Geschwulstforschung - 1 Jan 1990

Anders A, Anders F, Zechel C, Schleenbecker U, Smith A

Abstract excerpt

Certain backcross hybrids (BC8-22) of a spotted X. maculatus (platyfish) and a non-spotted X. helleri (swordtail; recurrent parent) are highly sensitive to mutagenic carcinogens and, after a latent period of 8 to 12 months, develop melanoma of unicellular origin that is genealogically related to...

Topics

Animals
Carcinogens
Cyprinodontiformes
Genes, Regulator
Hybridization, Genetic
Inositol
Melanoma, Experimental
Mutation
Oncogenes

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