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Article

Mate choice for more melanin as a mechanism to maintain a functional oncogene.

Proceedings of the National Academy of Sciences of the United States of America - 9 Sept 2008

Fernandez André A, Morris Molly R

Abstract excerpt

The mechanisms by which cancer evolves and persists in natural systems have been difficult to ascertain. In the Xiphophorus melanoma model, a functional oncogene (Xiphophorus melanoma receptor kinase Xmrk) has been maintained for several million years despite being deleterious and in an extremely unstable genomic region. Melanomas in Xiphophorus spp. fishes (platyfishes and swordtails) have been investigated...

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Identifiers

PMID: 18757731
DOI: 10.1073/pnas.0803851105
PMCID: PMC2533219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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