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Article

MNU induction of neoplasia in a platyfish model.

Laboratory investigation; a journal of technical methods and pathology - 1 Sept 2001

Kazianis S, Gimenez-Conti I, Setlow R B, Woodhead A D, Harshbarger J C, Trono D, Ledesma M, Nairn R S, Walter R B

Abstract excerpt

Interspecific hybrid crosses between members of the fish genus Xiphophorus have been used for over 70 years to study the genetic aspects of melanoma formation. In the well-established "Gordon-Kosswig" cross, the platyfish X. maculatus is outcrossed to the swordtail X. helleri, and the resulting backcross segregants spontaneously develop melanoma. We recently produced a distinct cross between X. maculatus and...

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Identifiers

PMID: 11555667
DOI: 10.1038/labinvest.3780333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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