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Article

Cdc7-Dbf4 regulates NDT80 transcription as well as reductional segregation during budding yeast meiosis.

Molecular biology of the cell - 1 Nov 2008

Lo Hsiao-Chi, Wan Lihong, Rosebrock Adam, Futcher Bruce, Hollingsworth Nancy M

Abstract excerpt

In budding yeast, as in other eukaryotes, the Cdc7 protein kinase is important for initiation of DNA synthesis in vegetative cells. In addition, Cdc7 has crucial meiotic functions: it facilitates premeiotic DNA replication, and it is essential for the initiation of recombination. This work uses a chemical genetic approach to demonstrate that Cdc7 kinase has additional roles in meiosis. First, Cdc7 allows...

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Identifiers

PMID: 18768747
DOI: 10.1091/mbc.e08-07-0755
PMCID: PMC2575173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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