Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of Ndt80, Sum1, and Swe1 as targets of the meiotic recombination checkpoint that control exit from pachytene and spore formation in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Sept 2002

Pak Julia, Segall Jacqueline

Abstract excerpt

The meiotic recombination checkpoint, which is triggered by defects in recombination or chromosome synapsis, arrests sporulating cells of Saccharomyces cerevisiae at pachytene by preventing accumulation of active Clb-Cdc28. We compared the effects of manipulating the three known targets of the meiotic recombination checkpoint, NDT80, SWE1, and SUM1, in dmc1-arrested cells. Ndt80 is an activator of a set of middle...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Cell Cycle Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fungal Proteins

Share to Meiosis

Share to Ploidies

Share to Protein-Tyrosine Kinases

Share to Repressor Proteins

Share to Spores, Fungal

Source

Open in PubMed Open full text

Identifiers

PMID: 12192042
DOI: 10.1128/MCB.22.18.6430-6440.2002
PMCID: PMC135635

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of Ndt80, Sum1, and Swe1 as targets of the meiotic recombination checkpoint that control exit from pachytene and spore formation in Saccharomyces cerevisiae.PMID 12192042Read ↗

The pachytene checkpoint in Saccharomyces cerevisiae requires the Sum1 transcriptional repressor.Semantic proximity Read ↗

The pachytene checkpoint in S. cerevisiae depends on Swe1-mediated phosphorylation of the cyclin-dependent kinase Cdc28.Semantic proximity Read ↗

Multisite phosphorylation of the Sum1 transcriptional repressor by S-phase kinases controls exit from meiotic prophase in yeast.Semantic proximity Read ↗

The Cdk1 and Ime2 protein kinases trigger exit from meiotic prophase in Saccharomyces cerevisiae by inhibiting the Sum1 transcriptional repressor.Semantic proximity Read ↗

Nuclear localization of the meiosis-specific transcription factor Ndt80 is regulated by the pachytene checkpoint.Semantic proximity Read ↗

Loss of meiotic rereplication block in Saccharomyces cerevisiae cells defective in Cdc28p regulation.Semantic proximity Read ↗

Saccharomyces cerevisiae C-type cyclin Ume3p/Srb11p is required for efficient induction and execution of meiotic development.Semantic proximity Read ↗

Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis.Semantic proximity Read ↗

Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae.Semantic proximity Read ↗

Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice.Semantic proximity Read ↗

Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks.Semantic proximity Read ↗

Direct and indirect control of the initiation of meiotic recombination by DNA damage checkpoint mechanisms in budding yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.