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Article

NDT80, a meiosis-specific gene required for exit from pachytene in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Dec 1995

Xu L, Ajimura M, Padmore R, Klein C, Kleckner N

Abstract excerpt

We describe the identification of a new meiosis-specific gene of Saccharomyces cerevisiae, NDT80. The ndt80 null and point mutants arrest at the pachytene stage of meiosis, with homologs connected by full-length synaptonemal complexes and spindle pole bodies duplicated but unseparated. Meiotic recombination in an ndt80 delta mutant is relatively normal, although commitment to heteroallelic recombination is...

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Identifiers

PMID: 8524222
DOI: 10.1128/MCB.15.12.6572
PMCID: PMC230910

Genes

RAD50
SPO11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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