Article
Nuclear localization of the meiosis-specific transcription factor Ndt80 is regulated by the pachytene checkpoint.
Molecular biology of the cell - 1 Jun 2011
Wang Ying, Chang Chun-Yu, Wu Jing-Fen, Tung Kuei-Shu
Abstract excerpt
In budding yeast, the Ndt80 protein is a meiosis-specific transcription factor that is essential for the exit of pachytene and progression into nuclear divisions and spore formation. The pachytene checkpoint responds to defects in meiotic recombination and chromosome synapsis and negatively regulates the activity of Ndt80. The activity of Ndt80 was suggested to be regulated at both transcriptional and...
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