Article
The Cdc14 Phosphatase Controls Resolution of Recombination Intermediates and Crossover Formation during Meiosis.
International journal of molecular sciences - 10 Sept 2021
Alonso-Ramos Paula, Álvarez-Melo David, Strouhalova Katerina, Pascual-Silva Carolina, Garside George B, Arter Meret, Bermejo Teresa, Grigaitis Rokas, Wettstein Rahel, Fernández-Díaz Marta, Matos Joao, Geymonat Marco, San-Segundo Pedro A, Carballo Jesús A
Abstract excerpt
Meiotic defects derived from incorrect DNA repair during gametogenesis can lead to mutations, aneuploidies and infertility. The coordinated resolution of meiotic recombination intermediates is required for crossover formation, ultimately necessary for the accurate completion of both rounds of chromosome segregation. Numerous master kinases orchestrate the correct assembly and activity of the repair machinery....
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