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Article

Regulation of the endosomal SNARE protein syntaxin 7 by colony-stimulating factor 1 in macrophages.

Molecular and cellular biology - 1 Oct 2008

Achuthan Adrian, Masendycz Paul, Lopez Jamie A, Nguyen Thao, James David E, Sweet Matthew J, Hamilton John A, Scholz Glen M

Abstract excerpt

Colony-stimulating factor 1 (CSF-1) is the main growth factor controlling the development of macrophages from myeloid progenitor cells. However, CSF-1 also regulates some of the key effector functions of macrophages (e.g., phagocytosis and cytokine secretion). The endosomal SNARE protein syntaxin 7 (Stx7) regulates vesicle trafficking events involved in phagocytosis and cytokine secretion. Therefore, we...

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Identifiers

PMID: 18710945
DOI: 10.1128/MCB.00220-08
PMCID: PMC2577439

Genes

VAMP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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