Article
Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.
The journal of physiological sciences : JPS - 1 May 2011
Tanaka Sayaka, Kabayama Hiroyuki, Enomoto Masahiro, Saito Nobuhito, Mikoshiba Katsuhiko
Abstract excerpt
Inositol 1, 4, 5-trisphosphate receptors (IP(3)Rs) are intracellular ligand-gated Ca(2+) channels that mediate Ca(2+) release from the endoplasmic reticulum (ER) into the cytosol and function in diverse cellular processes including fertilization, muscle contraction, apoptosis, secretion, and syna...
Topics
- Animals
- Binding Sites
- Calcium
- Cell Line
- Inositol 1,4,5-Trisphosphate Receptors
- Ion Channel Gating
- Ion Channels
- Mice
- Mutation
- PC12 Cells
- Protein Binding
- Protein Structure, Tertiary
- Rats
- SNARE Proteins
- Syntaxin 1