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Article

SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity.

BMC cell biology - 21 Nov 2012

Carrasquillo Robert, Tian Dequan, Krishna Sneha, Pollak Martin R, Greka Anna, Schlöndorff Johannes

Abstract excerpt

BACKGROUND: Transient receptor potential canonical (TRPC) channels are non-selective cation channels involved in receptor-mediated calcium signaling in diverse cells and tissues. The canonical transient receptor potential 6 (TRPC6) has been implicated in several pathological processes, including focal segmental glomerulosclerosis (FSGS), cardiac hypertrophy, and pulmonary hypertension. The two large cytoplasmic...

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Source

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Identifiers

PMID: 23171048
DOI: 10.1186/1471-2121-13-33
PMCID: PMC3520717

Genes

TRPC6
SNF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity.PMID 23171048Read ↗

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