Article
Association of the ABCG2 C421A polymorphism with prostate cancer risk and survival.
BJU international - 1 Dec 2008
Gardner Erin R, Ahlers Christoph M, Shukla Suneet, Sissung Tristan M, Ockers Sandra B, Price Douglas K, Hamada Akinobu, Robey Robert W, Steinberg Seth M, Ambudkar Suresh V, Dahut William L, Figg William D
Abstract excerpt
OBJECTIVE: To determine if the C421A single nucleotide polymorphism (SNP) in the ATP-binding cassette transporter ABCG2 increases prostate cancer risk or affects survival. PATIENTS, SUBJECTS AND METHODS: Numerous studies have suggested that dietary, hormonal and environmental factors all play a role in the initiation in prostate cancer; among these, the carcinogenic heterocyclic amine...
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