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Article

Contrasting roles of the ABCG2 Q141K variant in prostate cancer.

Experimental cell research - 1 May 2017

Sobek Kathryn M, Cummings Jessica L, Bacich Dean J, O'Keefe Denise S

Abstract excerpt

ABCG2 is a membrane transport protein that effluxes growth-promoting molecules, such as folates and dihydrotestosterone, as well as chemotherapeutic agents. Therefore it is important to determine how variants of ABCG2 affect the transporter function in order to determine whether modified treatment regimens may be necessary for patients harboring ABCG2 variants. Previous studies have demonstrated an association...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Recurrence, Local

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Source

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Identifiers

PMID: 28300564
DOI: 10.1016/j.yexcr.2017.03.020
PMCID: PMC5424544

Genes

ABCG2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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