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Article

Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer.

Cancer research - 1 Mar 2009

Koutros Stella, Berndt Sonja I, Sinha Rashmi, Ma Xiaomei, Chatterjee Nilanjan, Alavanja Michael C R, Zheng Tongzhang, Huang Wen-Yi, Hayes Richard B, Cross Amanda J

Abstract excerpt

We recently reported that heterocyclic amines (HCA) are associated with prostate cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. We now use extensive genetic data from this resource to determine if risks associated with dietary HCAs {2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP); 2-amino-3,8-dimethylimidazo[4,5-b]quinoxaline (MeIQx); and...

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Source

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Identifiers

PMID: 19223546
DOI: 10.1158/0008-5472.CAN-08-2447
PMCID: PMC2662592

Genes

GSTM3
GSTA1
GSTM1
GSTP1
NAT1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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