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Article

Frequent down-regulation of ABC transporter genes in prostate cancer

12 Oct 2015

Abstract excerpt

BACKGROUND: ATP-binding cassette (ABC) transporters are transmembrane proteins responsible for the efflux of a wide variety of substrates, including steroid metabolites, through the cellular membranes. For better characterization of the role of ABC transporters in prostate cancer (PCa) development, the profile of ABC transporter gene expression was analyzed in PCa and noncancerous prostate tissues (NPT). METHODS:...

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PMID: 26459268
DOI: 10.1186/s12885-015-1689-8

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