Article
Identification of novel SNPs associated with risk and prognosis in patients with castration-resistant prostate cancer.
Pharmacogenomics - 1 Dec 2016
Sissung Tristan M, Deeken John, Leibrand Crystal R, Price Douglas K, Ehrlich Sheryl, Steinberg Seth M, Liewehr David J, Dahut William, Figg William D
Abstract excerpt
AIM: Metabolism and transport play major roles in life-long exposure to endogenous and exogenous carcinogens. We therefore explored associations between polymorphisms in absorption, distribution, metabolism and elimination genes and the risk and prognosis of castration-resistant prostate cancer (CRPC). MATERIALS & METHODS: A total of 634 genotypes were tested in 74 patients using the Affymetrix DMETv1.0 platform....
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