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Article

Polymorphisms in the CYP1B1 gene are associated with increased risk of prostate cancer.

British journal of cancer - 20 Oct 2003

Chang B L, Zheng S L, Isaacs S D, Turner A, Hawkins G A, Wiley K E, Bleecker E R, Walsh P C, Meyers D A, Isaacs W B, Xu J

Abstract excerpt

CYP1B1 has been evaluated as a candidate gene for various cancers because of its function in activating environmental procarcinogens and catalysing the conversion of oestrogens to genotoxic catechol oestrogens. To test the hypothesis that genetic polymorphisms in the CYP1B1 gene may associate with the risk for prostate cancer (CaP), we compared the allele, genotype, and haplotype frequencies of 13 single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 14562027
DOI: 10.1038/sj.bjc.6601288
PMCID: PMC2394327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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