Article
Red wine consumption is inversely associated with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adduct levels in prostate.
Cancer prevention research (Philadelphia, Pa.) - 1 Oct 2011
Rybicki Benjamin A, Neslund-Dudas Christine, Bock Cathryn H, Nock Nora L, Rundle Andrew, Jankowski Michelle, Levin Albert M, Beebe-Dimmer Jennifer, Savera Adnan T, Takahashi Satoru, Shirai Tomoyuki, Tang Deliang
Abstract excerpt
In humans, genetic variation and dietary factors may alter the biological effects of exposure to 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), one of the major heterocyclic amines generated from cooking meats at high temperatures that has carcinogenic potential through the formation of DNA adducts. Previously, we reported grilled red meat consumption associated with PhIP-DNA adduct levels in human...
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