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Article

High-resolution copy number arrays in cancer and the problem of normal genome copy number variation.

Genes, chromosomes & cancer - 1 Nov 2008

Gorringe Kylie L, Campbell Ian G

Abstract excerpt

High-resolution techniques for analysis of genome copy number (CN) enable the analysis of complex cancer somatic genetics. However, the analysis of these data is difficult, and failure to consider a number of issues in depth may result in false leads or unnecessary rejection of true positives. First, segmental duplications may falsely generate CN breakpoints in aneuploid samples. Second, even when tumor data were...

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PMID: 18663746
DOI: 10.1002/gcc.20595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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