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Article

Dual regulation of Mad2 localization on kinetochores by Bub1 and Dam1/DASH that ensure proper spindle interaction.

Molecular biology of the cell - 1 Sept 2008

Saitoh Shigeaki, Kobayashi Yasuyo, Ogiyama Yuki, Takahashi Kohta

Abstract excerpt

The spindle assembly checkpoint monitors the state of spindle-kinetochore interaction to prevent premature onset of anaphase. Although checkpoint proteins, such as Mad2, are localized on kinetochores that do not interact properly with the spindle, it remains unknown how the checkpoint proteins recognize abnormalities in spindle-kinetochore interaction. Here, we report that Mad2 localization on kinetochores in...

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Identifiers

PMID: 18632983
DOI: 10.1091/mbc.e08-03-0298
PMCID: PMC2526710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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