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Article

Spindle checkpoint signaling requires the mis6 kinetochore subcomplex, which interacts with mad2 and mitotic spindles.

Molecular biology of the cell - 1 Aug 2005

Saitoh Shigeaki, Ishii Kojiro, Kobayashi Yasuyo, Takahashi Kohta

Abstract excerpt

The spindle checkpoint coordinates cell cycle progression and chromosome segregation by inhibiting anaphase promoting complex/cyclosome until all kinetochores interact with the spindle properly. During early mitosis, the spindle checkpoint proteins, such as Mad2 and Bub1, accumulate at kinetochores that do not associate with the spindle. Here, we assess the requirement of various kinetochore components for the...

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Identifiers

PMID: 15930132
DOI: 10.1091/mbc.e05-01-0014
PMCID: PMC1182306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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