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Article

Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast.

PLoS genetics - 11 Jul 2008

Demogines Ann, Smith Erin, Kruglyak Leonid, Alani Eric

Abstract excerpt

Complex traits typically involve the contribution of multiple gene variants. In this study, we took advantage of a high-density genotyping analysis of the BY (S288c) and RM strains of Saccharomyces cerevisiae and of 123 derived spore progeny to identify the genetic loci that underlie a complex DNA repair sensitivity phenotype. This was accomplished by screening hybrid yeast progeny for sensitivity to a variety of...

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Identifiers

PMID: 18617998
DOI: 10.1371/journal.pgen.1000123
PMCID: PMC2440805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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