Article
Genetic dissection of complex traits in yeast: insights from studies of gene expression and other phenotypes in the BYxRM cross.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2009
Ehrenreich I M, Gerke J P, Kruglyak L
Abstract excerpt
The genetic basis of many phenotypes of biological and medical interest, including susceptibility to common human diseases, is complex, involving multiple genes that interact with one another and the environment. Despite decades of effort, we possess neither a full grasp of the general rules that govern complex trait genetics nor a detailed understanding of the genetic basis of specific complex traits. We have...
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