Article
A noncomplementation screen for quantitative trait alleles in saccharomyces cerevisiae.
G3 (Bethesda, Md.) - 1 Jul 2012
Kim Hyun Seok, Huh Juyoung, Riles Linda, Reyes Alejandro, Fay Justin C
Abstract excerpt
Both linkage and linkage disequilibrium mapping provide well-defined approaches to mapping quantitative trait alleles. However, alleles of small effect are particularly difficult to refine to individual genes and causative mutations. Quantitative noncomplementation provides a means of directly testing individual genes for quantitative trait alleles in a fixed genetic background. Here, we implement a genome-wide...
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