Article
High-resolution mapping of complex traits with a four-parent advanced intercross yeast population.
Genetics - 1 Nov 2013
Cubillos Francisco A, Parts Leopold, Salinas Francisco, Bergström Anders, Scovacricchi Eugenio, Zia Amin, Illingworth Christopher J R, Mustonen Ville, Ibstedt Sebastian, Warringer Jonas, Louis Edward J, Durbin Richard, Liti Gianni
Abstract excerpt
A large fraction of human complex trait heritability is due to a high number of variants with small marginal effects and their interactions with genotype and environment. Such alleles are more easily studied in model organisms, where environment, genetic makeup, and allele frequencies can be controlled. Here, we examine the effect of natural genetic variation on heritable traits in a very large pool of baker's...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.