Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic architecture of highly complex chemical resistance traits across four yeast strains.

PLoS genetics - 1 Jan 2012

Ehrenreich Ian M, Bloom Joshua, Torabi Noorossadat, Wang Xin, Jia Yue, Kruglyak Leonid

Abstract excerpt

Many questions about the genetic basis of complex traits remain unanswered. This is in part due to the low statistical power of traditional genetic mapping studies. We used a statistically powerful approach, extreme QTL mapping (X-QTL), to identify the genetic basis of resistance to 13 chemicals in all 6 pairwise crosses of four ecologically and genetically diverse yeast strains, and we detected a total of more...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Crosses, Genetic
Share to Drug Resistance, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Association Studies

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 22438822
DOI: 10.1371/journal.pgen.1002570
PMCID: PMC3305394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic architecture of highly complex chemical resistance traits across four yeast strains.PMID 22438822Read ↗

Dissection of genetically complex traits with extremely large pools of yeast segregants.Semantic proximity Read ↗

Pervasive context-dependent effects in the genetic architecture of complex and quantitative traits revealed by a powerful multiparent mapping population in yeastSemantic proximity Read ↗

Pervasive context-dependent effects in the genetic architecture of complex and quantitative traits revealed by a powerful multiparent mapping population in yeast.Semantic proximity Read ↗

Genetic architecture: dissecting the genetic basis of phenotypic variation.Semantic proximity Read ↗

Rare variants contribute disproportionately to quantitative trait variation in yeast.Semantic proximity Read ↗

The complex genetic and molecular basis of a model quantitative trait.Semantic proximity Read ↗

Genetic mapping of MAPK-mediated complex traits Across S. cerevisiae.Semantic proximity Read ↗

The Hidden Complexity of Mendelian Traits across Natural Yeast Populations.Semantic proximity Read ↗

The genetic architecture in Saccharomyces cerevisiae that contributes to variation in drug response to the antifungals benomyl and ketoconazole.Semantic proximity Read ↗

High-resolution mapping of complex traits with a four-parent advanced intercross yeast population.Semantic proximity Read ↗

Genetic dissection of MAPK-mediated complex traits across <i>S. cerevisiae</i>Semantic proximity Read ↗

Genome-scale analysis of interactions between genetic perturbations and natural variation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.