Article
Mapping Quantitative Trait Loci in Yeast.
Cold Spring Harbor protocols - 1 Aug 2017
Liti Gianni, Warringer Jonas, Blomberg Anders
Abstract excerpt
Natural Saccharomyces strains isolated from the wild differ quantitatively in molecular and organismal phenotypes. Quantitative trait loci (QTL) mapping is a powerful approach for identifying sequence variants that alter gene function. In yeast, QTL mapping has been used in designed crosses to map functional polymorphisms. This approach, outlined here, is often the first step in understanding the molecular basis...
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