Article

Complex trait analysis with a multi-species approach to disentangle genetic modulators of cellular growth phenotypes under disease-relevant treatments

2020-01-01

Abstract excerpt

Complex traits are phenotypes that are described quantitatively and typically have intricate polygenic inheritance. Herein, the cellular growth under genotoxic and mitochondrial-induced oxidative stress, which underlie tumorigenesis and Parkinson's Disease, were studied as complex traits. It was hypothesized that advanced yeast complex trait mapping could be developed and employed to study these traits. The yeast...

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Literature Corpus work: 6c8b44f3-760b-5940-9962-50b678aae08e
DOI: 10.25392/leicester.data.12656717.v1

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