Article
Hepatitis B virus mutations associated with in situ expression of hepatitis B core antigen, viral load and prognosis in chronic hepatitis B patients.
Pathology, research and practice - 1 Jan 2008
Zhu Rong, Zhang Hui-Ping, Yu Hui, Li Hua, Ling Yu-Qin, Hu Xi-Qi, Zhu Hong-Guang
Abstract excerpt
In this retrospective study, we investigated the prevalence and significance of mutations in part of the hepatitis B virus (HBV) x gene, and tried to clarify their relationship with clinicopathological or histopathological characteristics and prognosis in patients with chronic hepatitis B (CHB). A total of 83 consecutive CHB patients (1986-1994) were chosen for the present study. Sequence analysis was performed...
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