Article
Impacts of the Percentage of Basal Core Promoter Mutation on the Progression of Liver Fibrosis After Hepatitis B e Antigen Seroconversion.
The Journal of infectious diseases - 23 Apr 2021
Wu Jia-Feng, Chang Kai-Chi, Ni Yen-Hsuan, Hsu Hong-Yuan, Chang Mei-Hwei
Abstract excerpt
BACKGROUND: We investigated the relationships among the percentage of hepatitis B virus (HBV) mutations and liver fibrosis after hepatitis B e antigen (HBeAg) seroconversion. METHODS: We quantified the percentage of HBV mutants by pyrosequencing using serum samples obtained at inflammatory phase and after HBeAg seroconversion in 160 initially HBeAg-positive chronic HBV-infected patients. The relationships between...
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