Article
Hepatitis B virus genotype B with G1896A and A1762T/G1764A mutations is associated with hepatitis B related acute-on-chronic liver failure.
Journal of medical virology - 1 Sept 2011
Xiao Lei, Zhou Bin, Gao Hongbo, Ma Shiwu, Yang Guifeng, Xu Min, Abbott William G H, Chen Jinjun, Sun Jian, Wang Zhanhui, Hou Jinlin
Abstract excerpt
The existence of statistical associations between hepatitis B-related acute-on-chronic liver failure and both hepatitis B virus (HBV) genotype and mutations in the basal core promoter (BCP) and precore (PC) regions needs to be confirmed. A total of 322 patients with a chronic HBV infection, including 77 with hepatitis B-related acute-on-chronic liver failure, 109 with hepatocellular carcinoma (HCC) and 136 with...
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