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Article

Differential association of the COMT Val158Met polymorphism with clinical phenotypes in schizophrenia and bipolar disorder.

Schizophrenia research - 1 Aug 2008

Goghari Vina M, Sponheim Scott R

Abstract excerpt

Schizophrenia and bipolar disorder, although diagnostically separate, likely share elements of their genetic etiology. This study assessed whether the COMT Val158Met polymorphism has shared or specific associations with clinical phenotypes evident in schizophrenia and bipolar disorder. Schizophrenia and bipolar patients completed a clinical assessment encompassing premorbid functioning and current and lifetime...

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Source

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Identifiers

PMID: 18571901
DOI: 10.1016/j.schres.2008.05.015
PMCID: PMC3815559

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential association of the COMT Val158Met polymorphism with clinical phenotypes in schizophrenia and bipolar disorder.PMID 18571901Read ↗

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Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia.Semantic proximity Read ↗

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